RESUMEN
ABSTRACT Choroidal tuberculomas are present in patients with ocular tuberculosis. They usually occur in a patient with previous history of tuberculosis, and are rarely the initial presentation, with no prior systemic manifestations. We present a patient with unilateral choroidal tuberculoma as the initial presentation of presumed ocular tuberculosis, which enabled earlier initiation of treatment.
RESUMO Os tuberculomas de coroide apresentam-se em pacientes com tuberculose ocular. Geralmente, ocorrem em indivíduos com história prévia de tuberculose e raramente têm apresentação inicial sem manifestações sistêmicas anteriores. Relatamos o caso de um paciente com tuberculoma de coroide unilateral com apresentação inicial de tuberculose ocular presumida, permitindo o início mais precoce do tratamento.
Asunto(s)
Humanos , Femenino , Adulto , Tuberculoma/diagnóstico , Enfermedades de la Coroides/diagnóstico , Tuberculoma/tratamiento farmacológico , Angiografía con Fluoresceína , Enfermedades de la Coroides/tratamiento farmacológico , Uveítis Posterior/diagnóstico , Tuberculosis Ocular , Coroides/diagnóstico por imagen , Fondo de Ojo , Antituberculosos/uso terapéuticoRESUMEN
A 14 year old girl presented with a 6-month history of headaches and visual blurring. CT showed a right tentorial enhancing lesion. Angiogram showed no enhancement. Histopathological examination of the excised material was consistent with tuberculoma. The presentation of such unusual intracranial tuberculoma is reported and the literature reviewed on the subject.
Asunto(s)
Adolescente , Antituberculosos/uso terapéutico , Encefalopatías/tratamiento farmacológico , Quimioterapia Combinada , Femenino , Humanos , Isoniazida/uso terapéutico , Pirazinamida/uso terapéutico , Rifampin/uso terapéutico , Tomografía Computarizada por Rayos X , Tuberculoma/tratamiento farmacológicoRESUMEN
Intradural extramedullary (IDEM) tuberculoma of the spinal cord is uncommon entity and moreover, few reports have been documented on concurrent IDEM and intracranial tuberculomas. Authors report a case of IDEM spinal tuberculoma having intracranial lesion simultaneously. A 49-year-old woman suffered from paraparesis and urinary incontinence while being given medical treatment for tuberculous meningitis. Magnetic resonance imaging (MRI) revealed an IDEM mass lesion between the T1 and T2 spinal levels, and multiple intracranial tuberculous granulomas. Surgical resection of the IDEM tuberculoma followed by anti-tuberculous medication resulted in good outcome.
Asunto(s)
Femenino , Humanos , Encéfalo/diagnóstico por imagen , Estudios de Seguimiento , Imagen por Resonancia Magnética , Persona de Mediana Edad , Mycobacterium tuberculosis/aislamiento & purificación , Enfermedades de la Médula Espinal/diagnóstico por imagen , Tuberculoma/cirugía , Tuberculoma/diagnóstico por imagen , Tuberculoma/tratamiento farmacológico , Tuberculoma/complicaciones , Tuberculosis Meníngea/cirugía , Tuberculosis Meníngea/diagnóstico por imagen , Tuberculosis Meníngea/tratamiento farmacológico , Tuberculosis Meníngea/complicacionesRESUMEN
A case of tuberculous meningitis with paradoxical progression to multiple brain tuberculoma and drug resistance during treatment has been described. Initially the patient presented as tuberculous meningitis with presence of AFB in CSF. CT scan of brain with controstenhancement revealed no abnormality on admission [5th October 1995]. Patient showed improvement clinically during chemotherapy but subsequently she developed total blindness due to bilateral primary optic atrophy. CT scan [6th November 1995] revealed hydrocephalus with left parietal lobe tuberculoma. V-P shunt was introduced [11th November 1995]. Follow-up CT scan was again done [7th March 1996], as the patient suddenly deteriorated, which detected bilateral multiple tuberculoma in brain. CSF study [21st March 1996] yielded AFB which was resistant to streptomycin and INH. New chemotherapy consisting of rifampicin, INH, pyrazinamide, PAS and ethionamide was continued for one year. Repeat CT scan [18th April 1996] detected regression of previous lesions. Last CSF study was normal. Patient's vision improved significantly though she had optic atrophy
Asunto(s)
Humanos , Femenino , Tuberculosis del Sistema Nervioso Central/tratamiento farmacológico , Tuberculosis Resistente a Múltiples Medicamentos , Progresión de la Enfermedad , Tuberculosis Meníngea , Tuberculoma/tratamiento farmacológico , Encéfalo/patologíaAsunto(s)
Antituberculosos/uso terapéutico , Niño , Relación Dosis-Respuesta a Droga , Esquema de Medicación , Quimioterapia Combinada , Femenino , Humanos , Tomografía Computarizada por Rayos X , Tuberculoma/tratamiento farmacológico , Tuberculosis Meníngea/tratamiento farmacológico , Tuberculosis Miliar/tratamiento farmacológico , Tuberculosis Pulmonar/tratamiento farmacológicoRESUMEN
Se presenta el caso de una paciente con un tuberculoma hepático producido por Mycobacterium fortuitum. La paciente fue curada con cirurgía y un esquema de antibiótico consiste amikacina y doxiciclina. Este caso constituye la primera publicación de un tuberculoma hepático producido por Mycobacterium fortuitum
Asunto(s)
Persona de Mediana Edad , Humanos , Femenino , Micobacterias no Tuberculosas/aislamiento & purificación , Tuberculoma/microbiología , Tuberculosis Hepática/microbiología , Amicacina/uso terapéutico , Doxiciclina/uso terapéutico , Quimioterapia Combinada , Tuberculoma/tratamiento farmacológico , Tuberculosis Hepática/tratamiento farmacológicoRESUMEN
Se presenta el caso de una enferma de 34 años de edad que presentó un tuberculoma cerebral asociado a una tuberculosis pulmonar. Fue tratado con éxito con isoniazida, estreptomicina, pirazinamida y etambutol sin requerir tratamiento local (intratecal o intra-ventricular). Su curación se relacionó con el uso de esteroides en altas dosis y por tiempo prolongado. Se señalan los riesgos del tratamiento quirúrgico. Se destaca la respuesta obtenida con el tratamiento médico a pesar de presentar la enferma varias características que sugieren, según la literatura, la nececidad de una exploración quirúrgica